Dynamic Devices

The Dynamic Devices Oasis liquid handler is used with the 96 1000 µL Head to perform protein purifications using the PhyTip columns. The system can use either 10 µL, 200 µL or 1000 µL tips on the same head within the same run for pipetting large or small volumes.
The drive system of the head makes it a perfect fit for the PhyTip application since the drive can aspirate and dispense at extremely slow speeds, from 2-5 µL/sec, giving the sample the capture time needed to expose it to the solid phase matrix in order for optimal binding and elution.

With a small footprint of 24 inches, the Oasis LM600 has 18 positions for processing PhyTip columns. Deck layouts include: PhyTip 1000 µL Tips, Standard 1000 uL Tips, Deepwell Sample Plates, Deepwell Elution Plates, Column Prep Reagent Reservoir, Deepwell Wash Buffer 1, Deepwell Wash Buffer 2, Elution Buffer Reservoir Deepwell plates are used to prevent cross contamination between samples during washing protocols and a Setup Run method can transfer Wash Buffers 1 & 2 from a reservoir to the deepwells and then removed to make more room for to process the samples with the PhyTip columns.

For more walk away time, the Oasis LM1200 offers 42 positions to process PhyTip columns. Combine the extra deck positions with 1-2 liter ‘fedder’ reservoirs to hold the wash buffers and triple the capacity. Additional configurations include dual 96 1000 µL Heads to process PhyTip simultaneously and gripper tools to move plates on and off the deck from storage containers and microplate readers, and a virtual ‘manufacturing line’ can be realized.

PhyNexus tips used with our proprietary Dual Flow Chromatography provide complete antibody binding for highly concentrated sample recovery from small samples.

Tecan Robotics

Tecan is a leading global provider of laboratory instruments and solutions in biopharmaceuticals, forensics, and clinical diagnostics. The company specializes in the development, production and distribution of instruments and automated workflow solutions for laboratories in the life sciences sector. The Freedom EVO® robotic workstation is the foundation for liquid handling in Tecan’s product portfolio. The Freedom EVO series offers four different worktable capacities (75, 100, 150 and 200 cm) each with building-block modularity that brings precision, reliable liquid handling and easy-to-use robotics. Each platform can be combined with a wide choice of robotic arms, liquid handling tools and application options powered by straightforward software to meet individual needs and the upgradeable Freedom EVO platform can evolve with ever changing application needs.

The Tecan PhyTip columns are designed and fully tested to work with the Freedom EVO® platforms, equipped with 8 and 96 channels. The combination of Tecan’s robotic integration and liquid handling expertise together with the innovative PhyTip columns gives the user a fully automated protein purification system for higher throughput demands. Up to 96 purifications can be performed in as little as 15 minutes in a walk-away manner. The system addresses the processing of both native and recombinant proteins and other analytes like carbohydrates, with low cross-contamination, high reproducibility, and highly robust processing. Standard and custom chromatography media can be packed into the PhyTip® columns, giving the customer the highest flexibility in the choice of their purification methods.

PhyNexus provides a host of solutions compatible with Dynamic Devices robotics to deliver 96-channel, high throughput solutions including:

Learn about automation solutions for Dynamic Devices Robotics

Select your resin, robotic system, tip and resin volume and see the results in the table below.

Dynamic Devices Columns

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