We have partnerships with major robotics companies & can find the right solution
PhyNexus MEA 2
The PhyNexus MEA 2 robot is a bench top 96 well format platform that brings cost effective sample prep right into the researcher’s lab. The MEA 2 fills the productivity gap between semi-automated instruments and 96 channel capability robots. When used with the unique PhyTip Cover, elution plates retain the integrity of the final elution at volumes as low as 10 µL to guarantee high concentrations of ultra-high purity samples. With the dedicated cooling system option, the MEA can be utilized on any standard lab bench without the need to occupy limited cold room space. The MEA 2 system offers the following:
- Automated programming of a 12 channel system
- Easy conversion from 200 µL to 1000 µL system
- Variable plate positions
- Easy to use software programming – the software is versatile and sophisticated so that it can be programmed for any type of method and chemistry for proteins and plasmids
- Complete automation
- Flexibility
The MEA 2 processes 12 samples in parallel, moving down the 8 rows of a plate, giving a powerful advantage over 96-at-a-time robots. Purification conditions can be surveyed to produce optimized capture, wash, and elution of any protein. Side-by-side comparisons along the row of 12 can be made with different conditions moving down each of the 8 rows. After conditions have been surveyed and chosen, the MEA 2 can be programmed to process one or two boxes of 96 samples with the optimized conditions.
Agilent Technologies
As the world’s premier measurement company, Agilent works in close collaboration with engineers, scientists, and researchers around the globe to meet the communications, electronics, life sciences, and chemical analysis challenges of today and tomorrow. The company operates two primary businesses – electronic and bio-analytical measurement – supported by Agilent Research Laboratories, its central research group. Agilent is committed to providing innovative measurement solutions that enable our customers and partners – the leaders in their fields – to deliver the products and services that make a measurable difference in the lives of people everywhere. From standalone units to fully integrated systems, Agilent teams key sample preparation and creative walk-away automation approaches with personalized customer service to provide complete solutions for your laboratory. Combining innovative engineering with high standards of quality, Agilent designs and manufactures high-performance equipment for processes that are revolutionizing pharmaceutical, biotech, and genomic research. The Agilent Bravo Automated Liquid Handling Platform is the fastest and most versatile small footprint liquid-handling system available. Two Bravo Platform models are available: standard and SRT. The standard model fits in most standard laminar flow hoods. The SRT model is three inches (7.62 cm) shorter, providing extra clearance for hoods with short internal height.
The PhyTip columns are designed and fully tested to work with the Agilent Bravo platforms, equipped with 96 channels. PhyNexus columns used with our proprietary Dual Flow Chromatography provide complete antibody binding for highly concentrated sample recovery from small samples. The combination of the innovative PhyTip columns with Agilent’s robotic integration and liquid handling expertise together gives the user a fully automated protein purification system for higher throughput demands. Up to 96 purifications can be performed in as little as 15 minutes in a walk-away manner. The system addresses the processing of both native and recombinant proteins and other analytes like carbohydrates, with low cross-contamination, high reproducibility, and highly robust processing. Standard and custom chromatography media can be packed into the PhyTip columns, giving the customer the highest flexibility in the choice of their purification methods.
Beckman Coulter
Beckman Coulter develops, manufactures, and markets products that simplify, automate and innovate complex biomedical testing. Scientists use these life science research instruments to study complex biological problems including causes of disease and potential new therapies or drugs. By offering a full range of flexible automation systems from system-based automation all the way through custom solutions, Beckman Coulter can offer laboratories multiple points of entry into the realm of automation. And with proven expertise at analyzing laboratory processes, can help guide each lab toward the automation level that is most appropriate and cost-efficient for its individual needs. Knowing that the ability to adapt to changing situations is critical for today’s labs, these systems are designed with the flexibility to accommodate whatever your needs may be. Build your Biomek system to handle today’s requirements, make modifications as necessary, add accessories whenever and wherever extra capability is important, and use a wide variety of modules to manage tomorrow’s needs with specifically targeted solutions. From standalone to industrial robotics solutions, the Biomek 3000, Biomek NXP, and the Biomek FXP liquid handling systems offer the most advanced and flexible liquid handler systems available.
The PhyTip columns are designed and fully tested to work with the Beckman Coulter platforms, equipped with 8 and 96 channels. The combination of the innovative PhyTip columns with Beckman Coulter’s robotic integration and liquid handling expertise together gives the user a fully automated protein purification system for higher throughput demands. Up to 96 purifications can be performed in as little as 15 minutes in a walk-away manner. The system addresses the processing of both native and recombinant proteins and other analytes like carbohydrates, with low cross-contamination, high reproducibility, and highly robust processing. Standard and custom chromatography media can be packed into the PhyTip columns, giving the customer the highest flexibility in the choice of their purification methods.
Dynamic Devices
The Dynamic Devices Oasis liquid handler is used with the 96 1000 µL Head to perform protein purifications using the PhyTip columns. The system can use either 10 µL, 200 µL or 1000 µL tips on the same head within the same run for pipetting large or small volumes.
The drive system of the head makes it a perfect fit for the PhyTip application since the drive can aspirate and dispense at extremely slow speeds, from 2-5 µL/sec, giving the sample the capture time needed to expose it to the solid phase matrix in order for optimal binding and elution.
With a small footprint of 24 inches, the Oasis LM600 has 18 positions for processing PhyTip columns. Deck layouts include: PhyTip 1000 µL Tips, Standard 1000 uL Tips, Deepwell Sample Plates, Deepwell Elution Plates, Column Prep Reagent Reservoir, Deepwell Wash Buffer 1, Deepwell Wash Buffer 2, Elution Buffer Reservoir Deepwell plates are used to prevent cross contamination between samples during washing protocols and a Setup Run method can transfer Wash Buffers 1 & 2 from a reservoir to the deepwells and then removed to make more room for to process the samples with the PhyTip columns.
For more walk away time, the Oasis LM1200 offers 42 positions to process PhyTip columns. Combine the extra deck positions with 1-2 liter ‘fedder’ reservoirs to hold the wash buffers and triple the capacity. Additional configurations include dual 96 1000 µL Heads to process PhyTip simultaneously and gripper tools to move plates on and off the deck from storage containers and microplate readers, and a virtual ‘manufacturing line’ can be realized.
Hamilton
As the world leader in robotic workstation innovation, Hamilton sets the standards for reliability, performance, and flexibility. The STAR line workstations are based on superior air displacement pipetting technology. This increases accuracy and repeatability while providing chain of custody with pipette condition monitoring and recording. Each workstation can be configured with multiple arms and each arm can be configured with multiple pipetting and labware gripping devices. Pipetting channels and labware grippers move independently of each other, supporting the use of a wide range of labware. The compact STARlet can be converted on-site to a STARplus by means of an extension module, more than doubling deck capacity. Thanks to the scalability of the STAR line instruments, the widest possible range of throughputs and budgets can be accommodated, it is even possible to add a second pipetting arm working in parallel.
PhyNexus PhyTip® columns are designed and fully tested to work with the Hamilton platforms, equipped with 8 channels. The combination of the innovative PhyTip columns with Hamilton’s robotic integration and liquid handling expertise together gives the user a fully automated protein purification system for higher throughput demands.
PhyNexus tips used with our proprietary Dual Flow Chromatography provide complete antibody binding for highly concentrated sample recovery from small samples. The system addresses the processing of both native and recombinant proteins and other analytes like carbohydrates, with low cross-contamination, high reproducibility, and highly robust processing. Standard and custom chromatography media can be packed into the PhyTip columns, giving you the highest flexibility in the choice of your purification methods.
Perkin Elmer
PerkinElmer designs, manufactures and delivers advanced technology solutions that address the world’s most critical health and safety concerns, including maternal and fetal health, clean water and air, and safe food and toys. Their expertise combines science, innovation and a culture of operational excellence to offer customers technology services and support that improve the quality of people’s lives worldwide. As your lab automation partner, PerkinElmer offers a wide array of liquid handling instruments and custom integration solutions to support and guide your research while increasing your efficiency and precision. The JANUS® Automated Workstation is easy to use and flexible to grow with your changing requirements in throughput, chemistries and application needs. The MiniTrak MPD Systems are a family of high throughput/high capacity systems for automated liquid handling. The MiniTrak’s unique MultiPosition Dispense Module (MPD) integrates a multi-position labware deck with highly precise dispense head positioning to facilitate reliable and accurate pipetting into 96 or more well microplates. PerkinElmer offers three models of MiniTrak systems, MiniTrak VE, MiniTrak VIII, and MiniTrak IX.
The PhyTip® columns are designed and fully tested to work with the Perkin Elmer platforms, equipped with 96 channels. The combination of the innovative PhyTip columns with PerkinElmer’s robotic integration and liquid handling expertise together gives the user a fully automated protein purification system for higher throughput demands. Up to 96 purifications can be performed in as little as 15 minutes in a walk-away manner. The system addresses the processing of both native and recombinant proteins and other analytes like carbohydrates, with low cross-contamination, high reproducibility, and highly robust processing. Standard and custom chromatography media can be packed into the PhyTip columns, giving the customer the highest flexibility in the choice of their purification methods.
Tecan
Tecan is a leading global provider of laboratory instruments and solutions in biopharmaceuticals, forensics, and clinical diagnostics. The company specializes in the development, production and distribution of instruments and automated workflow solutions for laboratories in the life sciences sector. The Freedom EVO® robotic workstation is the foundation for liquid handling in Tecan’s product portfolio. The Freedom EVO series offers four different worktable capacities (75, 100, 150 and 200 cm) each with building-block modularity that brings precision, reliable liquid handling and easy-to-use robotics. Each platform can be combined with a wide choice of robotic arms, liquid handling tools and application options powered by straightforward software to meet individual needs and the upgradeable Freedom EVO platform can evolve with ever changing application needs.
The Tecan PhyTip columns are designed and fully tested to work with the Freedom EVO® platforms, equipped with 8 and 96 channels. The combination of Tecan’s robotic integration and liquid handling expertise together with the innovative PhyTip columns gives the user a fully automated protein purification system for higher throughput demands. Up to 96 purifications can be performed in as little as 15 minutes in a walk-away manner. The system addresses the processing of both native and recombinant proteins and other analytes like carbohydrates, with low cross-contamination, high reproducibility, and highly robust processing. Standard and custom chromatography media can be packed into the PhyTip® columns, giving the customer the highest flexibility in the choice of their purification methods.
PhyNexus AutoPlasmid MMG
Fully-automated, two-channel, benchtop instrument for walk-away maxi, mega and gigaprep plasmid purification.
The AutoPlasmid MMG is the industry’s first and only fully-automated benchtop instrument for transfection quality plasmid purification at the maxi, mega and gigaprep scales. It delivers a robust and flexible solution that is capable of working with LB or TB media, one-touch or customizable methods, and delivering maxi, mega or gigaprep scale transfection quality plasmids. The AutoPlasmid MMG allows research laboratories to increase productivity of lab specialists, improve results through automation, and remove the tedium of manual plasmid preps. The AutoPlasmid MMG takes about 5-10 minutes to set up, then hit “start,” and walk away until your plasmids are ready.