PhyNexus Customers AMGEN, MERCK, GSK, EMD SERONO, LILLY, GENENTECH

Our customers are

companies and research groups

that touch people’s lives.

Fully Automated Plasmid Purification

Maxiprep, Megaprep and Gigaprep

We provide the chemistry to fit your automation research needs.

PhyNexus advanced manufacturing provides

exactly what you want when you need it.

We can pack virtually any resin into

all common robotic liquid handler pipette tips.

Fully Automated Gel Filtration for

Compatible with all major robotics

Remove >95% of salts with >80% yield of protein

Buffer Exchange & Desalting

96 sample format for HTP

Want to

automate your application

and don't know where to start?

We can find you the right solution through our

partnerships with major robotics companies.

PhyNexus Automation. Faster Research. Better Research.

PhyNexus provides life science researchers automation solutions to high throughput sample processing in drug discovery and screening using our Dual Flow Chromatography technology.

Publication: Semiautomated Small-Scale Purification Method for High-Throughput Expression Analysis of Recombinant Proteins. Book: High-Throughput Protein Production and Purification - Methods and Protocols Publication: Perfusion cell culture for the production of conjugated recombinant fusion proteins reduces clipping and quality heterogeneity compared to batch-mode processes. Publication: Salivary N-glycosyalation as a biomarker of Oral Cancer: A pilot study. Publication: Shedding Light into the Subcutis: A Mass Spectrometry Based Immunocapture Assay Enabling Full Characterization of Therapeutic Antibodies after Injection in Vivo.

Automated Plasmid Prep

Fully automated, two-channel, bench-top instrument for walk-away maxiprep, megaprep and gigaprep plasmid purification.

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PhyTip Columns Catalog

Our PhyTip columns work with all 8, 12, and 96 channel liquid handling high throughput robotics.

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PhyTip-columns-HTP-automation-96-samples-in-15-minutes

Automation Robotics

PhyNexus Phytip columns are available for all major HTP liquid handling high throughput robotics.

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Applications

The PhyTip column technology is a platform technology that can be directed to many different applications.

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Compatible Robots
Agilent Technologies
Analytik Jena
Beckman Coulter
Dynamic Devices
Hamilton Robotics
Opentrons
Perkin Elmer
Tecan Robotics

Want to automate your application with robotics in your lab & don’t know where to start?

We have partnerships with major robotics companies & can find the right solution
for automating your high throughput applications.

We can provide the right automation solution for your application, provide method & protocol development, support, installation, and training.

PhyNexus PhyTip Columns are compatible with most 8, 12, and 96-channel automation liquid handling robots including Agilent Technologies, Analytik Jena, Beckman Coulter, Dynamic Devices, Perkin Elmer, Hamilton, Tecan and Opentrons.

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“We have been using PhyTips to purify protein variants of several enzyme libraries in our high-throughput screening approach. The possibility of using automation protocols to obtain protein of high purity in 96-well format increased our throughput and efficiency immensely. PhyNexus’ customer service and technical support has been outstanding, and the staff has been responsive and very knowledgeable when helping us establish purification protocols. Moreover, PhyNexus was very supportive in addressing specific needs for our enzymes, providing highly reliable products of outstanding quality.”

Dr. Barbara EckertPrincipal Scientist, Roche Molecular Systems, Inc., Diagnostics

“Ever since they started up, PhyNexus has been providing my research group with high quality separation media, in a format that continues to exceed our expectations. When combined with automation, their innovative approaches and impressively responsive support systems, have made us into loyal customers! For me PhyNexus epitomizes an organization that not only demonstrates innovation, but understands the challenges faced by the user/customer and provides solutions that are both powerful and great value for money.”

Professor David HornbyDepartment of Molecular Biology and Biotechnology, University of Sheffield

“Our group has purified some of our proteins with your amazing tips. The result is fantastic! We are running binding assays and do not need much. The proteins have very good quality for binding assays.”

Dr. Heique BogdawaSenior Scientist at Phylogica, Drug Discovery Group, Perth, Australia

“Using the PNGase F functionalized microcolumns from PhyNexus, we obtained very efficient deglycosylation in 10 min with excellent reproducibility and the option for full automation. Using this approach is crucial if the presence of the digestion enzyme represents a problem after the glycan release, e.g., when the remaining protein is further interrogated by mass spectrometry. The support of PhyNexus during the development of the assay was exceptional.”

Professor András GuttmanHead of Horváth Csaba Laboratory of Bioseparation Sciences, University of Debrecen, Hungary

“PhyNexus tip technology is a very reliable and enabling technology for high throughput purification. The technical support and scientific expertise in this company is second to none”

Dr. Olivier DalmasScientist II, Biologics, NGM Biopharmaceuticals, USA

“I use the PhyNexus MEA system for discovery research applications for over 10 years now. Immunoprecipitations for Western Blot, protein concentration or purification from tissue extracts and cell culture supernatants and more. The system is straight forward, versatile, reliable and completely adjustable to the conditions I need and I can change the protocols and methods easily to fit my needs. It works for high throughput equally well as for “never-done-before, give-it-a-try” assays. Plus, as far as I am concerned, they offer the best customer service on the planet!”

Dr. Claudia FiegerResearch Scientist at Macrogenics, USA

“Our team purifies glycoproteins from bloods and serum using PhyNexus tips, using both pre-packed tips and custom tips on an automated handling system. We observe repeatable, reproducible results and high purity every time. The advantage of using the tip technology over traditional plate formats for our application is that we can extract multiple proteins/glycoproteins from the one clinical sample, expanding our assays for life sciences discovery.”

Dr. Roisin O’FlahertyPost Doctoral Research Fellow at National Institute for Bioprocessing Research and Training, Dublin, Ireland

We Specialize in

automated protein & plasmid purification.

Get up to

95% yields

with PhyTip Columns on your robot!

Any sample volume, any column size, scalable, and reproducible

Our customers are

companies and research groups

that touch people’s lives.

AutoPlasmid MMG

Fully Automated Plasmid Purification

Maxiprep, Megaprep and Gigaprep

Transfection Grade Plasmids

Hands-Free Walk Away

WATCH THE VIDEO

We provide the chemistry to fit your automation research needs.

PhyNexus advanced manufacturing provides

exactly what you want when you need it.

We can pack virtually any resin into

all common robotic liquid handler pipette tips.

Fully Automated Gel Filtration for

Compatible with all major robotics

Remove >95% of salts with >80% yield of protein

Buffer Exchange & Desalting

96 sample format for HTP

Want to

automate your application

and don't know where to start?

We can find you the right solution through our

partnerships with major robotics companies.

PhyNexus Automation. Faster Research. Better Research.

PhyNexus provides life science researchers automation solutions to high throughput sample processing in drug discovery and screening using our Dual Flow Chromatography technology.

Automated Plasmid Prep

PhyTip Columns Catalog

Automation Robotics

Applications

Want to automate your application with robotics in your lab & don’t know where to start?

We have partnerships with major robotics companies & can find the right solution for automating your high throughput applications.

We can provide the right automation solution for your application, provide method & protocol development, support, installation, and training.

PhyNexus PhyTip Columns are compatible with most 8, 12, and 96-channel automation liquid handling robots including Agilent Technologies, Analytik Jena, Beckman Coulter, Dynamic Devices, Perkin Elmer, Hamilton, Tecan and Opentrons.

Plasmids

Desalting Gel Filtration

Dual Flow Chromatography

Bench-top Robotic MEA 2

Products

Products Catalogs

Applications

PhyTip Columns for Robots

Technology

About PhyNexus

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We have partnerships with major robotics companies & can find the right solution
for automating your high throughput applications.